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2020年版WHO胆囊与肝外胆管肿瘤组织学分类

a.    Benign epithelial tumor/precursors良性上皮性肿瘤/前驱病变

                                          i.    Adenoma

腺瘤

                                         ii.    Biliary intraepithelial neoplasia胆管上皮内瘤变

1.    Biliary intraepithelial neoplasia,Low-grade

胆管上皮内瘤变,低级别

2.    Biliary intraepithelial neoplasia,High-grade

胆管上皮内瘤变,高级别

                                        iii.    Intracystic papillary neoplasm胆囊内乳头状肿瘤

1.    Intracystic papillary neoplasm,Low-grade

胆囊内乳头状肿瘤,低级别

2.    Intracystic papillary neoplasm,High-grade

胆囊内乳头状肿瘤,高级别

3.    With associated invasive adenocarcinoma

伴有浸润性腺癌

                                       iv.    Intraductal papillary neoplasm胆管内乳头状肿瘤

1.    Intraductal papillary neoplasm,Low-grade

胆管内乳头状肿瘤,低级别

2.    Intraductal papillary neoplasm,High-grade

胆管内乳头状肿瘤,高级别

3.    With associated invasive adenocarcinoma

伴有浸润性腺癌

b.    Malignant epithelial tumors恶性上皮性肿瘤

                                          i.    Adenocarcinoma腺癌

1.    Adenocarcinoma, intestinal type

腺癌,肠型

2.    PSL adenocarcinoma

PSL腺癌

3.    Mucinous cystic neoplasm with associated invasive carcinoma

黏液囊性肿瘤伴浸润性癌

4.    Mucinous adenocarcinoma

黏液腺癌

5.    Poorly cohesive carcinoma

低黏附性癌

6.    Intracystic papillary neoplasm with associated invasive carcinoma

囊内乳头状肿瘤伴有浸润性癌

                                         ii.    Squamous cell carcinoma

鳞状细胞癌

                                        iii.    Carcinoma, undifferentiated

未分化癌

                                       iv.    Adenosquamous carcinoma

腺鳞癌

                                        v.    Cholangiocarcinoma

胆管细胞癌

                                       vi.    Neuroendocrine tumor神经内分泌肿瘤

1.    Neuroendocrine tumor, grade 1

神经内分泌肿瘤,G1

2.    Neuroendocrine tumor, grade 2

神经内分泌肿瘤,G2

3.    Neuroendocrine tumor, grade 3

神经内分泌肿瘤,G3

                                      vii.    Neuroendocrine carcinoma神经内分泌癌

1.    Large cell neuroendocrine carcinoma

大细胞神经内分泌癌

2.    Small cell neuroendocrine carcinoma

小细胞神经内分泌癌

                                     viii.    Mixed neuroendocrine–non-–neuroendocrine neoplasm (MiNEN)

混合性神经内分泌-非神经内分泌肿瘤


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